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Saa1/Saa2tm1Itl
Targeted Allele Detail
Nomenclature
Symbol: Saa1/Saa2tm1Itl
Name: serum amyloid A 1; targeted mutation 1, inGenious Targeting Laboratory
MGI ID: MGI:4838092
Synonyms: SAA1.1/SAA2.1-, Saa1/Saa2tm1Igl
Gene: Saa1  Location: Chr7:46740501-46742980 bp, - strand  Genetic Position: Chr7, 30.54 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165605
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (C57BL/6NTac x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion
 
Mutation details10.1 kb spanning both gene, including exons 1 and 2 of each gene, and the intervening sequence was replaced with a loxP/FRT-flanked neo cassette. The absence of protein expression was confirmed by western blot analysis. (J:165605)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Saa1 Mutation:  0 strains or lines available
References
Original:  J:165605 de Beer MC, et al., Impact of serum amyloid A on High Density Lipoprotein composition and levels. J Lipid Res. 2010 Nov;51(11):3117-25
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory