Tlr8/Tlr7^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Tlr8/Tlr7^tm1Vlcg
• Name: toll-like receptor 8; targeted mutation 1, Velocigene
• MGI ID: MGI:4837832
• Gene: Tlr8 Location: ChrX:166025692-166047325 bp, - strand Genetic Position: ChrX, 78.29 cM, cytoband F5
• Alliance: Tlr8/Tlr7^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165267
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intergenic deletion
• Tlr8/Tlr7^tm1Vlcg involves 2 genes/genome features (Tlr8, Tlr7) View all
• Mutation details: Most of the coding region of each gene as well as the 70 kb interveining sequence was replaced with a lacZ gene. (J:102090)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tlr8 Mutation: 11 strains or lines available

Notes

Embryonic stem cells used to generate this allele are either CJ7 (129S1/Sv), F1H4 ((129 x C57BL/6)/F1), RW4 (129X1/SvJ), or an unnamed C57BL/6 line. (J:102090)

References

• Original: J:102090 Valenzuela DM, et al., High-throughput engineering of the mouse genome coupled with high-resolution expression analysis. Nat Biotechnol. 2003 Jun;21(6):652-9
• All: 6 reference(s)