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Serpinb2tm2Dgi
Targeted Allele Detail
Nomenclature
Symbol: Serpinb2tm2Dgi
Name: serine (or cysteine) peptidase inhibitor, clade B, member 2; targeted mutation 2, David Ginsburg
MGI ID: MGI:4837545
Synonyms: PAI-2-, SerpinB215B11-
Gene: Serpinb2  Location: Chr1:107511423-107535478 bp, + strand  Genetic Position: Chr1, 50.34 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:52283
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exons 3-8. Western analysis of cultured monocytes did not detect immunoreactive protein in homozygous mutant mice. (J:52283)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Serpinb2 Mutation:  15 strains or lines available
References
Original:  J:52283 Dougherty KM, et al., The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):686-91
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/13/2017
MGI 6.10
The Jackson Laboratory