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Jak2tm1(JAK2)Argr
Targeted Allele Detail
Nomenclature
Symbol: Jak2tm1(JAK2)Argr
Name: Janus kinase 2; targeted mutation 1, Anthony R Green
MGI ID: MGI:4836590
Synonyms: JAK2F, JAK2V617F
Gene: Jak2  Location: Chr19:29251828-29313080 bp, + strand  Genetic Position: Chr19, 23.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:164539
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Jak2 Mutation:  5 strains or lines available
References
Original:  J:164539 Li J, et al., JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F-positive essential thrombocythemia. Blood. 2010 Sep 2;116(9):1528-38
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory