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Tg(MMTV-PTGS2)#Thla
Transgene Detail
Nomenclature
Symbol: Tg(MMTV-PTGS2)#Thla
Name: transgene insertion, Timothy Hla
MGI ID: MGI:4834855
Synonyms: MMTV-COX-2
Transgene: Tg(MMTV-PTGS2)#Thla  Location: unknown  
Transgene
origin
Strain of Origin:  CD-1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe mouse mammary tumor virus promoter drives expression of human PTGS2. Three founders were created, but no line numbers were provided. Low levels of transgene expression were detected in the mammary gland in mature virgin females and expression levels were significantly induced during pregnancy and lactation. (J:68565)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:68565 Liu CH, et al., Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem. 2001 May 25;276(21):18563-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory