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Clcn5tm6.2Tjj
Targeted Allele Detail
Nomenclature
Symbol: Clcn5tm6.2Tjj
Name: chloride channel 5; targeted mutation 6.2, Thomas J Jentsch
MGI ID: MGI:4834489
Gene: Clcn5  Location: ChrX:7153810-7319358 bp, - strand  Genetic Position: ChrX, 3.21 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:164474
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exon 11 and 12. Western blot analysis confirmed the absence of protein expression. (J:164474)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clcn5 Mutation:  13 strains or lines available
References
Original:  J:164474 Rickheit G, et al., Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation. J Biol Chem. 2010 Jun 4;285(23):17595-603
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory