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Targeted Allele Detail
Symbol: Tardbptm1.2Pcw
Name: TAR DNA binding protein; targeted mutation 1.2, Philip C Wong
MGI ID: MGI:4834280
Synonyms: Tardp-
Gene: Tardbp  Location: Chr4:148612382-148627019 bp, - strand  Genetic Position: Chr4, 78.77 cM
Germline Transmission:  Earliest citation of germline transmission: J:164406
Parent Cell Line:  V26.2 (ES Cell)
Strain of Origin:  C57BL/6
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 3 was deleted in the germline by interbreeding Tardbptm1.1 heterozygous animals with Tg(CAG-cre)13Miya mice. (J:164406)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tardbp Mutation:  22 strains or lines available
Original:  J:164406 Chiang PM, et al., Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16320-4
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory