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Nusap1tm1.1Gcm
Targeted Allele Detail
Nomenclature
Symbol: Nusap1tm1.1Gcm
Name: nucleolar and spindle associated protein 1; targeted mutation 1.1, Geert Carmeliet
MGI ID: MGI:4833676
Gene: Nusap1  Location: Chr2:119618298-119651244 bp, + strand  Genetic Position: Chr2, 59.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:164315
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed neomycin selection cassette was inserted in intron 2 and a third loxP site was inserted in intron 3. The neomycin selection cassette and exon 3 were subsequently excised by transient cre expression from properly targeted ES cells. (J:164315)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nusap1 Mutation:  39 strains or lines available
References
Original:  J:164315 Vanden Bosch A, et al., NuSAP is essential for chromatin-induced spindle formation during early embryogenesis. J Cell Sci. 2010 Oct 1;123(Pt 19):3244-55
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory