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Smad4tm1.1Rdp
Targeted Allele Detail
Nomenclature
Symbol: Smad4tm1.1Rdp
Name: SMAD family member 4; targeted mutation 1.1, Ronald DePinho
MGI ID: MGI:4830314
Synonyms: Smad4-
Gene: Smad4  Location: Chr18:73639009-73703780 bp, - strand  Genetic Position: Chr18, 49.51 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:163858
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    LoxP sites were inserted to flank exons 8 and 9. Cre mediated recombination removed exons 8 and 9. (J:116139)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad4 Mutation:  12 strains or lines available
References
Original:  J:163858 Morsut L, et al., Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo. Development. 2010 Aug 1;137(15):2571-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory