Zfat^tm1Sawa
Targeted Allele Detail

Summary

• Symbol: Zfat^tm1Sawa
• Name: zinc finger and AT hook domain containing; targeted mutation 1, Senji Shirasawa
• MGI ID: MGI:4829941
• Gene: Zfat Location: Chr15:67955613-68130705 bp, - strand Genetic Position: Chr15, 29.44 cM
• Alliance: Zfat^tm1Sawa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163605
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 1.4 kb fragment including exon 8 was replaced with a neo resistance cassette via homologous recombination. (J:163605)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfat Mutation: 73 strains or lines available

References

• Original: J:163605 Tsunoda T, et al., Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islands. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14199-204
• All: 1 reference(s)