About   Help   FAQ
Esr1tm1.1Pws
Targeted Allele Detail
Nomenclature
Symbol: Esr1tm1.1Pws
Name: estrogen receptor 1 (alpha); targeted mutation 1.1, Philip W Shaul
MGI ID: MGI:4829939
Gene: Esr1  Location: Chr10:4611989-5005633 bp, + strand  Genetic Position: Chr10, 2.03 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:163783
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Cre mediated recombination removed exon 3. The absence of expression was confirmed in all tissues. (J:163783)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Esr1 Mutation:  14 strains or lines available
References
Original:  J:163783 Chambliss KL, et al., Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. J Clin Invest. 2010 Jul 1;120(7):2319-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/07/2020
MGI 6.15
The Jackson Laboratory