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Targeted Allele Detail
Symbol: Cdkn2btm1Wff
Name: cyclin dependent kinase inhibitor 2B; targeted mutation 1, Linda Wolff
MGI ID: MGI:4829849
Gene: Cdkn2b  Location: Chr4:89306299-89311039 bp, - strand  Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
Germline Transmission:  Earliest citation of germline transmission: J:163498
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsExon 2 was floxed and a neo cassette with a an additional 3' loxP site was inserted within intron 2 by homologous recombination. (J:163498)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdkn2b Mutation:  3 strains or lines available
Original:  J:163498 Bies J, et al., Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia. Blood. 2010 Aug 12;116(6):979-87
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory