About   Help   FAQ
Cdkn2btm1Wff
Targeted Allele Detail
Nomenclature
Symbol: Cdkn2btm1Wff
Name: cyclin dependent kinase inhibitor 2B; targeted mutation 1, Linda Wolff
MGI ID: MGI:4829849
Gene: Cdkn2b  Location: Chr4:89306299-89311039 bp, - strand  Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:163498
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 2 was floxed and a neo cassette with a an additional 3' loxP site was inserted within intron 2 by homologous recombination. (J:163498)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdkn2b Mutation:  3 strains or lines available
References
Original:  J:163498 Bies J, et al., Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia. Blood. 2010 Aug 12;116(6):979-87
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/31/2020
MGI 6.15
The Jackson Laboratory