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Col4a1ENU4004
Chemically induced Allele Detail
Summary
Symbol: Col4a1ENU4004
Name: collagen, type IV, alpha 1; ENU mutation 4004
MGI ID: MGI:4822148
Synonyms: Col4a1G394V
Gene: Col4a1  Location: Chr8:11248423-11362826 bp, - strand  Genetic Position: Chr8, 5.53 cM
Alliance: Col4a1ENU4004 page
Mutation
origin
Strain of Origin:  DBA/2
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsMale mice were exposed to 80 mg/kg body weight of ENU. This resulted in a G to T nucleotide substitution a position 1312 (NCBI accession # NM_009931) which caused a Glycine to Valine substitution at amino acid residue 394. (J:163225)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Col4a1 Mutation:  77 strains or lines available
References
Original:  J:63651 Favor J, et al., Saturation mutagenesis for dominant eye morphological defects in the mouse Mus musculus. Mamm Genome. 2000 Jul;11(7):520-5
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory