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Mks1avc6
Chemically induced Allele Detail
Nomenclature
Symbol: Mks1avc6
Name: Meckel syndrome, type 1; atrioventricular canal 6
MGI ID: MGI:4821832
Gene: Mks1  Location: Chr11:87853215-87863803 bp, + strand  Genetic Position: Chr11, 52.24 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU) (Null/knockout)
Mutation:    Single point mutation
 
Mutation detailsThe causative mutation is a nonsense mutation, C-to-T transition at g.87853328. The C-to-T transition results in an arginine being converted to a premature stop codon, p.Arg27*. (J:237132)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mks1 Mutation:  10 strains or lines available
References
Original:  J:163196 Kamp A, et al., Genome-wide identification of mouse congenital heart disease loci. Hum Mol Genet. 2010 Aug 15;19(16):3105-13
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory