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Tg(TcraCN.B1,TcrbCN.B1)SM1Jen
Transgene Detail
Nomenclature
Symbol: Tg(TcraCN.B1,TcrbCN.B1)SM1Jen
Name: transgene insertion SM1, Marc K Jenkins
MGI ID: MGI:4821793
Synonyms: SM1 TCR
Transgene: Tg(TcraCN.B1,TcrbCN.B1)SM1Jen  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(TcraCN.B1,TcrbCN.B1)SM1Jen expresses 2 genes
 
Mutation detailsTransgenic mice express a TCR from the T cell clone CN.B1, specific for Salmonella typhimurium flagellin peptide (427-441)-I-Ab, a TCR composed of Valpha10Jalpha10 and Vbeta2Dbeta1Jbeta1.2. The recombined TCR clone is expressed in T lymphocytes. (J:135513)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:135513 McSorley SJ, et al., Tracking salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection. Immunity. 2002 Mar;16(3):365-77
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory