Tg(TcraCN.B1,TcrbCN.B1)SM1Jen
Transgene Detail

Summary

• Symbol: Tg(TcraCN.B1,TcrbCN.B1)SM1Jen
• Name: transgene insertion SM1, Marc K Jenkins
• MGI ID: MGI:4821793
• Synonyms: SM1 TCR
• Transgene: Tg(TcraCN.B1,TcrbCN.B1)SM1Jen Location: unknown
• Alliance: Tg(TcraCN.B1,TcrbCN.B1)SM1Jen page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(TcraCN.B1,TcrbCN.B1)SM1Jen expresses 2 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tcra (MGI:98553)
  mouse	Tcrb (MGI:98578)

• Mutation details: Transgenic mice express a TCR from the T cell clone CN.B1, specific for Salmonella typhimurium flagellin peptide (427-441)-I-Ab, a TCR composed of Valpha10Jalpha10 and Vbeta2Dbeta1Jbeta1.2. The recombined TCR clone is expressed in T lymphocytes. (J:135513)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:135513 McSorley SJ, et al., Tracking salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection. Immunity. 2002 Mar;16(3):365-77
• All: 15 reference(s)