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Targeted Allele Detail
Symbol: Kidins220tm1.1Mvc
Name: kinase D-interacting substrate 220; targeted mutation 1.1, Moses V Chao
MGI ID: MGI:4820793
Gene: Kidins220  Location: Chr12:24974925-25063152 bp, + strand  Genetic Position: Chr12, 8.54 cM
Germline Transmission:  Earliest citation of germline transmission: J:162839
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 14 and an FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 14. Cre mediated recombination removed exon 14 and the neo cassette. (J:162839)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kidins220 Mutation:  1 strain or line available
Original:  J:162839 Wu SH, et al., Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stability in vivo. Dev Neurobiol. 2009 Aug;69(9):547-57
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory