Yap1^tm1.2Dupa
Targeted Allele Detail

Summary

• Symbol: Yap1^tm1.2Dupa
• Name: yes-associated protein 1; targeted mutation 1.2, Duojia Pan
• MGI ID: MGI:4819827
• Synonyms: Yap^KO
• Gene: Yap1 Location: Chr9:7932000-8004597 bp, - strand Genetic Position: Chr9, 2.46 cM
• Alliance: Yap1^tm1.2Dupa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162628
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre mediated recombination removed exon 1 and 2. (J:162628)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Yap1 Mutation: 37 strains or lines available

References

• Original: J:162628 Zhang N, et al., The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Dev Cell. 2010 Jul 20;19(1):27-38
• All: 7 reference(s)