Lin9^tm1Sgau
Targeted Allele Detail

Summary

• Symbol: Lin9^tm1Sgau
• Name: lin-9 DREAM MuvB core complex component; targeted mutation 1, Stefan Gaubatz
• MGI ID: MGI:4819560
• Gene: Lin9 Location: Chr1:180468715-180518252 bp, + strand Genetic Position: Chr1, 84.46 cM
• Alliance: Lin9^tm1Sgau page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162678
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted around exon 7 and an FRT flanked beta-geo cassette was inserted downstream of exon 7. (J:162678)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lin9 Mutation: 49 strains or lines available

References

• Original: J:162678 Reichert N, et al., Lin9, a subunit of the mammalian DREAM complex, is essential for embryonic development, for survival of adult mice, and for tumor suppression. Mol Cell Biol. 2010 Jun;30(12):2896-908
• All: 1 reference(s)