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Ctcfltm1.1Vloc
Targeted Allele Detail
Nomenclature
Symbol: Ctcfltm1.1Vloc
Name: CCCTC-binding factor (zinc finger protein)-like; targeted mutation 1.1, Victor Lobanenkov
MGI ID: MGI:4819542
Synonyms: BORIS-(-neo)
Gene: Ctcfl  Location: Chr2:173093609-173119525 bp, - strand  Genetic Position: Chr2, 95.74 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:162590
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region of exon 1 through exon 8 was replaced with (5' to 3'): a loxP site, GFP, lox511 site, and FRT flanked neo cassette. Flp mediated recombination removed the neo cassette. (J:162590)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctcfl Mutation:  3 strains or lines available
References
Original:  J:162590 Suzuki T, et al., Expression of a testis-specific form of Gal3st1 (CST), a gene essential for spermatogenesis, is regulated by the CTCF paralogous gene BORIS. Mol Cell Biol. 2010 May;30(10):2473-84
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory