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Tg(THY1-tTA)177Jpj
Transgene Detail
Nomenclature
Symbol: Tg(THY1-tTA)177Jpj
Name: transgene insertion 177, Jean-Pierre Julien
MGI ID: MGI:4819013
Synonyms: Tg(tTa)
Transgene: Tg(THY1-tTA)177Jpj  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F1
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsThe human promoter was used to drive neuron-specific expression of the tetracycline transactivator. Three lines were established. Line 177 expresses in the nervous system with highest in the cerebral cortex and spinal cord. (J:160704)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:160704 Dequen F, et al., Reversal of neuropathy phenotypes in conditional mouse model of Charcot-Marie-Tooth disease type 2E. Hum Mol Genet. 2010 Jul 1;19(13):2616-29
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory