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Tg(Emu-FGFR3)D3Wmk
Transgene Detail
Summary
Symbol: Tg(Emu-FGFR3)D3Wmk
Name: transgene insertion D3, W Michael Kuehl
MGI ID: MGI:4819001
Transgene: Tg(Emu-FGFR3)D3Wmk  Location: unknown  
Alliance: Tg(Emu-FGFR3)D3Wmk page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Emu-FGFR3)D3Wmk expresses 1 gene
 
Mutation detailsThe Emu enchancer and Lck proximal promoter drive B and T cell-specific expression of the human cDNA (FGFR3 IIIc isoform). Six founder mice (founders H1, D3, A5, and K1) were generated. (J:160845)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:160845 Zingone A, et al., Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms. Leukemia. 2010 Jun;24(6):1171-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory