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Targeted Allele Detail
Symbol: Slc6a9tm1Veul
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 9; targeted mutation 1, Volker Eulenburg
MGI ID: MGI:4818447
Synonyms: GlyT1(+)
Gene: Slc6a9  Location: Chr4:117834506-117875198 bp, + strand  Genetic Position: Chr4, 53.62 cM
Germline Transmission:  Earliest citation of germline transmission: J:161993
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA floxed neomycin selection cassette was inserted in intron 2 and a third loxP was inserted in intron 4. The neomycin selection cassette was subsequently removed by transient cre expression leaving exons 3 and 4 floxed. (J:161993)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc6a9 Mutation:  11 strains or lines available
Original:  J:161993 Eulenburg V, et al., Glial glycine transporter 1 function is essential for early postnatal survival but dispensable in adult mice. Glia. 2010 Jul;58(9):1066-73
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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