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Pik3r1tm2Dfr
Targeted Allele Detail
Nomenclature
Symbol: Pik3r1tm2Dfr
Name: phosphoinositide-3-kinase regulatory subunit 1; targeted mutation 2, David A Fruman
MGI ID: MGI:4818438
Synonyms: Pik3r1tm2Dfi
Gene: Pik3r1  Location: Chr13:101680563-101768217 bp, - strand  Genetic Position: Chr13, 53.92 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94077
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis mutation substitutes a neomycin resistance cassette for exon 7, the first exon common to the three alternative transcripts encoding the p85alpha, p55alpha and p50alpha regulatory subunits, and some flanking intronic DNA. (J:94077)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pik3r1 Mutation:  42 strains or lines available
References
Original:  J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory