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Targeted Allele Detail
Symbol: Pik3r1tm2Dfr
Name: phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); targeted mutation 2, David A Fruman
MGI ID: MGI:4818438
Synonyms: Pik3r1tm2Dfi
Gene: Pik3r1  Location: Chr13:101680563-101768217 bp, - strand  Genetic Position: Chr13, 53.92 cM
Germline Transmission:  Earliest citation of germline transmission: J:94077
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThis mutation substitutes a neomycin resistance cassette for exon 7, the first exon common to the three alternative transcripts encoding the p85alpha, p55alpha and p50alpha regulatory subunits, and some flanking intronic DNA. (J:94077)
Inheritance:    Semidominant
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pik3r1 Mutation:  20 strains or lines available
Original:  J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.01
The Jackson Laboratory