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Del(17Abcg1-Rrp1b)5Yey
Targeted Allele Detail
Nomenclature
Symbol: Del(17Abcg1-Rrp1b)5Yey
Name: deletion, Chr 17, Y Eugene Yu 5
MGI ID: MGI:4818361
Synonyms: Del(17)1Yey, Del(17Abcg1-Rrp1b)1Yey, Del5Yey, Df(17)1Yey, Df(Abcg1-Rrp1b)1Yey
Gene: Del(17Abcg1-Rrp1b)5Yey  Location: Chr17:31276672-32281839 bp  Genetic Position: Chr17, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161398
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion, Intragenic deletion
  Del(17Abcg1-Rrp1b)5Yey involves 28 genes/genome features (Gm25883, Gm25447, Gm24970 ...) View all
 
Mutation detailsCre mediated chromosomal rearrangement between loxP sites in regions proximal to Abcg1 and distal to Rrp1b resulted in the deletion of the genes, including Abcg1 and Rrp1b, in this approximately 1.1 Mb region that is syntenic with the proximal part of human 21q22.3. (J:161398)
Generation of the Del(17Abcg1-Rrp1b)5Yey deletion
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Del(17Abcg1-Rrp1b)5Yey Mutation:  1 strain or line available
References
Original:  J:161398 Yu T, et al., Deficiencies in the region syntenic to human 21q22.3 cause cognitive deficits in mice. Mamm Genome. 2010 Jun;21(5-6):258-67
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory