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Targeted Allele Detail
Symbol: Oaz3tm1Htan
Name: ornithine decarboxylase antizyme 3; targeted mutation 1, Hiromitsu Tanaka
MGI ID: MGI:4462794
Synonyms: OAZ-t-
Gene: Oaz3  Location: Chr3:94433387-94436651 bp, - strand  Genetic Position: Chr3, 40.66 cM, cytoband F2
Histological analysis and TUNEL staining of testicular sections of Oaz3tm1Htan/Oaz3+ and Oaz3tm1Htan/Oaz3tm1Htan testes

Show the 4 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:161751
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 1-5 were replaced with neo by homologous recombination. Northern and western blotting on testes lysates confirmed absence of transcripts and protein. This is a null allele. (J:161751)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Oaz3 Mutation:  16 strains or lines available
Original:  J:161751 Tokuhiro K, et al., OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse. PLoS Genet. 2009 Nov;5(11):e1000712
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory