About   Help   FAQ
Oaz3tm1Htan
Targeted Allele Detail
Nomenclature
Symbol: Oaz3tm1Htan
Name: ornithine decarboxylase antizyme 3; targeted mutation 1, Hiromitsu Tanaka
MGI ID: MGI:4462794
Synonyms: OAZ-t-
Gene: Oaz3  Location: Chr3:94432414-94443915 bp, - strand  Genetic Position: Chr3, 40.66 cM, cytoband F2
Histological analysis and TUNEL staining of testicular sections of Oaz3tm1Htan/Oaz3+ and Oaz3tm1Htan/Oaz3tm1Htan testes

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161751
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1-5 were replaced with neo by homologous recombination. Northern and western blotting on testes lysates confirmed absence of transcripts and protein. This is a null allele. (J:161751)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Oaz3 Mutation:  9 strains or lines available
References
Original:  J:161751 Tokuhiro K, et al., OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse. PLoS Genet. 2009 Nov;5(11):e1000712
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/18/2017
MGI 6.08
The Jackson Laboratory