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Targeted Allele Detail
Symbol: Add3tm1.2Llp
Name: adducin 3 (gamma); targeted mutation 1.2, Luanne Peters
MGI ID: MGI:4462017
Synonyms: gamma-adddeltaex2deltaneo
Gene: Add3  Location: Chr19:53140443-53247326 bp, + strand  Genetic Position: Chr19, 47.18 cM
Germline Transmission:  Earliest citation of germline transmission: J:161920
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThe floxed exon 2 was excised from Add3tm1.1Llp by mating with mice expressing cre recombinase. Western blotting confirmed the absence of the protein in the spleen. (J:161920)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Add3 Mutation:  8 strains or lines available
Original:  J:161920 Sahr KE, et al., Targeted deletion of the gamma-adducin gene (Add3) in mice reveals differences in alpha-adducin interactions in erythroid and nonerythroid cells. Am J Hematol. 2009 Jun;84(6):354-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.15
The Jackson Laboratory