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Olig2tm1.1(cre)Wdr
Targeted Allele Detail
Summary
Symbol: Olig2tm1.1(cre)Wdr
Name: oligodendrocyte transcription factor 2; targeted mutation 1.1, William D Richardson
MGI ID: MGI:4461156
Synonyms: Olig2-cre, Olig2-iCre
Gene: Olig2  Location: Chr16:91022345-91025565 bp, + strand  Genetic Position: Chr16, 52.6 cM
Alliance: Olig2tm1.1(cre)Wdr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161358
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Olig2tm1.1(cre)Wdr expression driven by 1 gene
 
Mutation detailsAn IRES-Cre-lox-PGK-Neo-lox cassette was introduced into the single exon of Olig2 in ES cells. The PGK-Neo was subsequently removed with cre. (J:161358)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Olig2 (mouse)
Summary of all recombinase alleles driven by Olig2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Olig2 Mutation:  46 strains or lines available
References
Original:  J:161358 Zawadzka M, et al., CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. Cell Stem Cell. 2010 Jun 4;6(6):578-90
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory