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Msh2tm2.1Rak
Targeted Allele Detail
Nomenclature
Symbol: Msh2tm2.1Rak
Name: mutS homolog 2 (E. coli); targeted mutation 2.1, Raju Kucherlapati
MGI ID: MGI:4460262
Synonyms: M2CKO, MSH2CKO, MSH2CKO pGKneo flipped ou, Msh2LoxP
Gene: Msh2  Location: Chr17:87672330-87723713 bp, + strand  Genetic Position: Chr17, 57.87 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161577
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Msh2 Mutation:  44 strains or lines available
References
Original:  J:161577 Kucherlapati MH, et al., An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents. Gastroenterology. 2010 Mar;138(3):993-1002.e1
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory