Tg(tetO-Creb1)5397Nes
Transgene Detail

Summary

• Symbol: Tg(tetO-Creb1)5397Nes
• Name: transgene insertion 5397, Eric Nestler
• MGI ID: MGI:4460238
• Synonyms: TetOp-CREB
• Transgene: Tg(tetO-Creb1)5397Nes Location: unknown
• Alliance: Tg(tetO-Creb1)5397Nes page

Transgene origin

• Strain of Origin: SJL/J x C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: The transgene contains the tet operon (tetO) and a minimal CMV promoter controlling expression of a cDNA encoding rat cAMP-responsive element binding protein 1 (CREB1), alpha isoform; the coding sequence is followed by the SV40 intron and polyadenylation signal. (J:92225, J:92951, J:128618)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92942 McClung CA, et al., Regulation of gene expression and cocaine reward by CREB and DeltaFosB. Nat Neurosci. 2003 Nov;6(11):1208-15
• All: 5 reference(s)