Fgfr3^tm6.1Cxd
Targeted Allele Detail

Summary

• Symbol: Fgfr3^tm6.1Cxd
• Name: fibroblast growth factor receptor 3; targeted mutation 6.1, Chu-Xia Deng
• MGI ID: MGI:4459833
• Gene: Fgfr3 Location: Chr5:33879068-33894412 bp, + strand Genetic Position: Chr5, 17.83 cM, cytoband B
• Alliance: Fgfr3^tm6.1Cxd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161199
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 9 and 10 were floxed and a neo cassette followed by a loxP site was inserted within intron 10 by homologous recombination. The selection cassette was removed by cre mediated recombination. The gene was shown to be properly transcribed by PCR. (J:161199)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfr3 Mutation: 52 strains or lines available

References

• Original: J:161199 Su N, et al., Generation of Fgfr3 conditional knockout mice. Int J Biol Sci. 2010;6(4):327-32
• All: 13 reference(s)