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Fpr2tm1.1Jimw
Targeted Allele Detail
Nomenclature
Symbol: Fpr2tm1.1Jimw
Name: formyl peptide receptor 2; targeted mutation 1.1, Ji Ming Wang
MGI ID: MGI:4459724
Synonyms: mFPR2neoloxp
Gene: Fpr2  Location: Chr17:17887824-17893952 bp, + strand  Genetic Position: Chr17, 10.66 cM, cytoband A3.1
Decreased colon crypt length in Fpr2tm1.1Jimw/Fpr2tm1.1Jimw Tg(Vil1-cre)997Gum/0 mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:160074
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upstream of the coding exon and an additional loxP site was inserted downstream of the coding exon. Cre mediated recombination removes the neo cassette leaving the coding exon floxed. (J:160074)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fpr2 Mutation:  2 strains or lines available
References
Original:  J:160074 Chen K, et al., A critical role for the g protein-coupled receptor mFPR2 in airway inflammation and immune responses. J Immunol. 2010 Apr 1;184(7):3331-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory