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Rpgrtm1Wbrg
Targeted Allele Detail
Nomenclature
Symbol: Rpgrtm1Wbrg
Name: retinitis pigmentosa GTPase regulator; targeted mutation 1, Wolfgang Berger
MGI ID: MGI:4458091
Synonyms: Rpgrdeltaexon4
Gene: Rpgr  Location: ChrX:10158216-10216795 bp, - strand  Genetic Position: ChrX, 4.62 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:160802
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 4 was replaced with a neo cassette. The absence of RNA transcripts containing exon 4 was confirmed by RT-PCR on retinal extracts. (J:160802)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rpgr Mutation:  2 strains or lines available
References
Original:  J:160802 Brunner S, et al., Cone versus rod disease in a mutant Rpgr mouse caused by different genetic backgrounds. Invest Ophthalmol Vis Sci. 2010 Feb;51(2):1106-15
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory