About   Help   FAQ
Adamts12tm1Agno
Targeted Allele Detail
Nomenclature
Symbol: Adamts12tm1Agno
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12; targeted mutation 1, Agnes Noel
MGI ID: MGI:4457760
Gene: Adamts12  Location: Chr15:11064790-11346867 bp, + strand  Genetic Position: Chr15, 5.43 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:160778
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 6 and 7 were replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR on ovary, mammary gland, uterus, lung, ear, and lymph node extracts. (J:160778)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adamts12 Mutation:  56 strains or lines available
References
Original:  J:160778 El Hour M, et al., Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis. Oncogene. 2010 May 20;29(20):3025-32
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory