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Zbtb167t
Chemically induced Allele Detail
Nomenclature
Symbol: Zbtb167t
Name: zinc finger and BTB domain containing 16; seven toes
MGI ID: MGI:4457499
Synonyms: 7t, Plzf7t
Gene: Zbtb16  Location: Chr9:48565597-48747522 bp, - strand  Genetic Position: Chr9, 26.47 cM
Limb and axial skeleton abnormalities in Zbtb167t/Zbtb167t mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis ENU induced mutation has an A to G transition at nucleotide 379 of the cDNA, which alters amino acid 44 from the polar and acidic amino acid glutamic acid into the nonpolar neutral amino acid glycine (Glu44Gly). This amino acid resides in the conserved BTB (Bric-a-brac, Tramtrack, Broad-complex) or POZ (Poxvirus zinc finger) domain of the gene. (J:160477)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 11 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Zbtb16 Mutation:  24 strains or lines available
References
Original:  J:160477 Ching YH, et al., An allele separating skeletal patterning and spermatogonial renewal functions of PLZF. BMC Dev Biol. 2010;10(1):33
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory