About   Help   FAQ
Targeted Allele Detail
Symbol: Dnm2tm1.1Pdc
Name: dynamin 2; targeted mutation 1.1, Pietro De Camilli
MGI ID: MGI:4457365
Synonyms: Dnm2LoxP
Gene: Dnm2  Location: Chr9:21424908-21507759 bp, + strand  Genetic Position: Chr9, 7.79 cM
Germline Transmission:  Earliest citation of germline transmission: J:161127
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (C57BL/6 x 129S1/SvImJ)F1
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 2 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Flp mediated recombination removed the neo cassette leaving exon 2 floxed. (J:161127)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dnm2 Mutation:  88 strains or lines available
Original:  J:161127 Ferguson SM, et al., Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits. Dev Cell. 2009 Dec;17(6):811-22
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.16
The Jackson Laboratory