Fgf10^tm1.2Sms
Targeted Allele Detail

Summary

• Symbol: Fgf10^tm1.2Sms
• Name: fibroblast growth factor 10; targeted mutation 1.2, Suzanne L Mansour
• MGI ID: MGI:4456398
• Synonyms: Fgf10^c, Fgf10^fl
• Gene: Fgf10 Location: Chr13:118851199-118928651 bp, + strand Genetic Position: Chr13, 67.14 cM, cytoband A3-A4
• Alliance: Fgf10^tm1.2Sms page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160254
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Flp mediated recombination removed the neo cassette leaving exon 2 floxed. (J:160254)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fgf10 Mutation: 33 strains or lines available

References

• Original: J:160254 Urness LD, et al., FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a. Dev Biol. 2010 Apr 15;340(2):595-604
• All: 11 reference(s)