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Fgf10tm1.2Sms
Targeted Allele Detail
Nomenclature
Symbol: Fgf10tm1.2Sms
Name: fibroblast growth factor 10; targeted mutation 1.2, Suzanne L Mansour
MGI ID: MGI:4456398
Synonyms: Fgf10c, Fgf10fl
Gene: Fgf10  Location: Chr13:118851235-118929109 bp, + strand  Genetic Position: Chr13, 67.14 cM, cytoband A3-A4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:160254
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Flp mediated recombination removed the neo cassette leaving exon 2 floxed. (J:160254)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgf10 Mutation:  23 strains or lines available
References
Original:  J:160254 Urness LD, et al., FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a. Dev Biol. 2010 Apr 15;340(2):595-604
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory