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Gmnntm1.2Kio
Targeted Allele Detail
Nomenclature
Symbol: Gmnntm1.2Kio
Name: geminin; targeted mutation 1.2, Dimitris Kioussis
MGI ID: MGI:4456373
Gene: Gmnn  Location: Chr13:24751845-24761923 bp, - strand  Genetic Position: Chr13, 10.64 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159657
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed the neo cassette, exon 3 and exon 4. The absence of protein expression was confirmed by western blot analysis on thymus and spleen extracts. (J:159657)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gmnn Mutation:  5 strains or lines available
References
Original:  J:159657 Karamitros D, et al., Differential geminin requirement for proliferation of thymocytes and mature T cells. J Immunol. 2010 Mar 1;184(5):2432-41
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory