About   Help   FAQ
Tmem204tm1.1Ali
Targeted Allele Detail
Summary
Symbol: Tmem204tm1.1Ali
Name: transmembrane protein 204; targeted mutation 1.1, Kari Alitalo
MGI ID: MGI:4454669
Gene: Tmem204  Location: Chr17:25276676-25300088 bp, - strand  Genetic Position: Chr17, 12.53 cM
Alliance: Tmem204tm1.1Ali page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159519
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted 5' to exon 1 and an FRT flanked neomycin cassette followed by a loxP site was inserted within intron 1. Exon 1 has been removed by cre-mediated recombination. Absence of transcript was confirmed by RT-PCR. (J:159519)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 70 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmem204 Mutation:  14 strains or lines available
References
Original:  J:159519 Saharinen P, et al., Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes Dev. 2010 May;24(9):875-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory