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Tmem204tm1.1Ali
Targeted Allele Detail
Nomenclature
Symbol: Tmem204tm1.1Ali
Name: transmembrane protein 204; targeted mutation 1.1, Kari Alitalo
MGI ID: MGI:4454669
Gene: Tmem204  Location: Chr17:25057702-25081114 bp, - strand  Genetic Position: Chr17, 12.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159519
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted 5' to exon 1 and an FRT flanked neomycin cassette followed by a loxP site was inserted within intron 1. Exon 1 has been removed by cre-mediated recombination. Absence of transcript was confirmed by RT-PCR. (J:159519)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmem204 Mutation:  9 strains or lines available
References
Original:  J:159519 Saharinen P, et al., Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes Dev. 2010 May;24(9):875-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory