Sox11^tm2.1Weg
Targeted Allele Detail

Summary

• Symbol: Sox11^tm2.1Weg
• Name: SRY (sex determining region Y)-box 11; targeted mutation 2.1, Michael Wegner
• MGI ID: MGI:4454340
• Synonyms: Sox11^fl
• Gene: Sox11 Location: Chr12:27384263-27392573 bp, - strand Genetic Position: Chr12, 9.95 cM, cytoband A3
• Alliance: Sox11^tm2.1Weg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157923
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the coding region. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of the coding region. Flp-mediated recombination removed the neo cassette and left the coding region floxed. (J:175338)

Expression

In Mice Carrying this Mutation:

2 assay results 3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox11 Mutation: 14 strains or lines available

References

• Original: J:157923 Potzner MR, et al., Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system. Development. 2010 Mar;137(5):775-84
• All: 18 reference(s)