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Arg1tm1.1Lky
Targeted Allele Detail
Nomenclature
Symbol: Arg1tm1.1Lky
Name: arginase, liver; targeted mutation 1.1, Richard M Locksley
MGI ID: MGI:4453214
Synonyms: Arg1Yarg, Arg1YFP, YARG
Gene: Arg1  Location: Chr10:24791105-24803368 bp, - strand  Genetic Position: Chr10, 12.26 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122735
Parent Cell Line:  PC3 (ES Cell)
Strain of Origin:  129S4/SvJae-Tg(Prm-cre)70Og
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsAn IRES element linked to an enhanced YFP construct was inserted in exon 8 downstream of the endogenous stop codon and a floxed neomycin cassette. The neomycin selection cassette was excised in male mice by cre expressed from the Prm1 promoter. (J:122735)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Arg1 Mutation:  21 strains or lines available
References
Original:  J:122735 Reese TA, et al., Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature. 2007 May 3;447(7140):92-6
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory