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Tg(Myh6-STK4)28Jusa
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-STK4)28Jusa
Name: transgene insertion 28, Junichi Sadoshima
MGI ID: MGI:4452338
Synonyms: Tg-Mst1, Tg(Myh6-MST1)28Jusa
Transgene: Tg(Myh6-STK4)28Jusa  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-STK4)28Jusa expresses 1 gene
 
Mutation detailsThe mouse promoter drives cardiac-specific expression of the human cDNA. Two lines were created (line 28 and 8) with line 28 exhibiting high levels of expression and line 8 intermediate levels of expression. (J:139414)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:139414 Yamamoto S, et al., Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy. J Clin Invest. 2003 May;111(10):1463-74
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory