Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Ruslan Medzhltov |
MGI ID: |
MGI:4443071 |
Synonyms: |
R26-mp53delta |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz page
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Germline Transmission: |
Earliest citation of germline transmission:
J:158953
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Note |
mouse |
Trp53 (MGI:98834) |
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Mutation details: Cre mediated recombination removed the floxed neo cassette allowing ubiquitous and moderate expression of the mutated cDNA and EGFP.
(J:158953)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
942 strains or lines available
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Original: |
J:158953 Bondar T, et al., p53-mediated hematopoietic stem and progenitor cell competition. Cell Stem Cell. 2010 Apr 2;6(4):309-22 |
All: |
1 reference(s) |
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