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Gad1tm1.1Bgc
Targeted Allele Detail
Nomenclature
Symbol: Gad1tm1.1Bgc
Name: glutamate decarboxylase 1; targeted mutation 1.1, Brian G Condie
MGI ID: MGI:4442416
Synonyms: Gad1lacZ
Gene: Gad1  Location: Chr2:70561765-70602014 bp, + strand  Genetic Position: Chr2, 41.63 cM, cytoband D
Umbilical hernia in Gad1tm1.1Bgc/Gad1tm1.1Bgc mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158888
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA cassette containing LacZ and a floxed MC1Neo was inserted into exon 2 producing an in frame fusion via homologous recombination. The neo was removed by Cre mediated recombination. (J:159165)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gad1 Mutation:  18 strains or lines available
References
Original:  J:159165 Westmoreland JJ, et al., Neuronal development of embryonic stem cells: a model of GABAergic neuron differentiation. Biochem Biophys Res Commun. 2001 Jun 15;284(3):674-80
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory