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Terf2iptm1.2Tdl
Targeted Allele Detail
Nomenclature
Symbol: Terf2iptm1.2Tdl
Name: telomeric repeat binding factor 2, interacting protein; targeted mutation 1.2, Titia de Lange
MGI ID: MGI:4441596
Synonyms: Rap1deltaex
Gene: Terf2ip  Location: Chr8:112011359-112020528 bp, + strand  Genetic Position: Chr8, 58.29 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158884
Parent Cell Line:  CY2.4 (ES Cell)
Strain of Origin:  B6(Cg)-Tyrc-2J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exon 2. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts. (J:158884)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Terf2ip Mutation:  17 strains or lines available
References
Original:  J:158884 Sfeir A, et al., Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal. Science. 2010 Mar 26;327(5973):1657-61
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory