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Ccl17tm1.1Ifo
Targeted Allele Detail
Summary
Symbol: Ccl17tm1.1Ifo
Name: C-C motif chemokine ligand 17; targeted mutation 1.1, Irmgard Foerster
MGI ID: MGI:4441162
Synonyms: CCL17E, CCL17/EGFP
Gene: Ccl17  Location: Chr8:95537081-95538664 bp, + strand  Genetic Position: Chr8, 46.85 cM
Alliance: Ccl17tm1.1Ifo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159098
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsEGFP, polyadenylation sequence, and an frt flanked neo cassette were inserted into exon 2. Flp mediated recombination removed the neo cassette. The absence of protein expression was confirmed by ELISA on bone marrow-derived dendritic cells. (J:159098)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccl17 Mutation:  7 strains or lines available
References
Original:  J:159098 Alferink J, et al., Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J Exp Med. 2003 Mar 3;197(5):585-99
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory