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Targeted Allele Detail
Symbol: Alas1tm1.1Mym
Name: aminolevulinic acid synthase 1; targeted mutation 1.1, Masayuki Yamamoto
MGI ID: MGI:4440831
Synonyms: Alas1GFP
Gene: Alas1  Location: Chr9:106233455-106248126 bp, - strand  Genetic Position: Chr9, 57.46 cM, cytoband F1
Germline Transmission:  Earliest citation of germline transmission: J:158435
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA EGFP and floxed neo caseette were inserted upstream of exon 2. Cre mediated recombination removed the neo cassette. Transcript levels in the liver and testis are unaffected in heterozygous mice. (J:158435)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Alas1 Mutation:  30 strains or lines available
Original:  J:158435 Okano S, et al., Indispensable function for embryogenesis, expression and regulation of the nonspecific form of the 5-aminolevulinate synthase gene in mouse. Genes Cells. 2010 Jan;15(1):77-89
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
The Jackson Laboratory