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Tg(PDGFB-Adra2b)13Hag
Transgene Detail
Nomenclature
Symbol: Tg(PDGFB-Adra2b)13Hag
Name: transgene insertion 13, Haralambos Gavras
MGI ID: MGI:4440595
Synonyms: TG13
Transgene: Tg(PDGFB-Adra2b)13Hag  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(PDGFB-Adra2b)13Hag expresses 1 gene
 
Mutation detailsThe transgenic construct contained the mouse alpha 2b adrenergic receptor followed by a human growth hormone polyA signal under the control of a human platelet-derived growth factor-beta chain promoter (PDGFB). Three founder lines (10, 13, and 16) were established. (J:158792)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:158792 Kintsurashvili E, et al., Hypertension in transgenic mice with brain-selective overexpression of the alpha(2B)-adrenoceptor. Am J Hypertens. 2009 Jan;22(1):41-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory