About   Help   FAQ
Hdac2tm1.2Pmt
Targeted Allele Detail
Nomenclature
Symbol: Hdac2tm1.2Pmt
Name: histone deacetylase 2; targeted mutation 1.2, Patrick Matthias
MGI ID: MGI:4440562
Gene: Hdac2  Location: Chr10:36974544-37001889 bp, + strand  Genetic Position: Chr10, 19.44 cM, cytoband B1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157903
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 6 was floxed and a neo cassette with a 3' loxP site was inserted within intron 7.The selection cassette and exon 6 were removed by cre mediated recombination. (J:157903)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hdac2 Mutation:  27 strains or lines available
References
Original:  J:157903 Yamaguchi T, et al., Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. Genes Dev. 2010 Mar 1;24(5):455-69
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/11/2020
MGI 6.14
The Jackson Laboratory