About   Help   FAQ
Targeted Allele Detail
Symbol: Hdac2tm1.2Pmt
Name: histone deacetylase 2; targeted mutation 1.2, Patrick Matthias
MGI ID: MGI:4440562
Gene: Hdac2  Location: Chr10:36974544-37001889 bp, + strand  Genetic Position: Chr10, 19.44 cM, cytoband B1
Germline Transmission:  Earliest citation of germline transmission: J:157903
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 6 was floxed and a neo cassette with a 3' loxP site was inserted within intron 7.The selection cassette and exon 6 were removed by cre mediated recombination. (J:157903)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hdac2 Mutation:  27 strains or lines available
Original:  J:157903 Yamaguchi T, et al., Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. Genes Dev. 2010 Mar 1;24(5):455-69
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory