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Tg(CAG-VCP*A232E)93Jpat
Transgene Detail
Nomenclature
Symbol: Tg(CAG-VCP*A232E)93Jpat
Name: transgene insertion 93, J Paul Taylor
MGI ID: MGI:4440440
Synonyms: VCP-A232E
Transgene: Tg(CAG-VCP*A232E)93Jpat  Location: unknown  
Transgene
origin
Strain of Origin:  SJL
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-VCP*A232E)93Jpat expresses 1 gene
 
Mutation detailsThe CAG promoter was used to drive ubiquitous expression of the human cDNA with a nucleotide substitution resulting in the amino acid substitution of glutamic acid for alanine at position 93 (A232E). Five lines were created with line 93 selected as the representative line. (J:158713)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:158713 Custer SK, et al., Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone. Hum Mol Genet. 2010 May 1;19(9):1741-55
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory