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Agap2tm1.1Kye
Targeted Allele Detail
Nomenclature
Symbol: Agap2tm1.1Kye
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; targeted mutation 1.1, Keqiang Ye
MGI ID: MGI:4439325
Synonyms: PIKE-
Gene: Agap2  Location: Chr10:127078907-127093169 bp, + strand  Genetic Position: Chr10, 74.5 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158376
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exons 3 through 6. The absence of protein expression was confirmed by western blot analysis on mammary gland extracts. (J:158376)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Agap2 Mutation:  25 strains or lines available
References
Original:  J:158376 Chan CB, et al., PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development. EMBO J. 2010 Mar 3;29(5):956-68
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory